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tecovirimat will increase the stage or outcome of diazepam by impacting hepatic enzyme CYP2C19 metabolism. Use Warning/Observe. Tecovirimat is actually a weak inhibitor of CYP2C8 and CYP2C19. Keep track of for adverse outcomes if coadministered with delicate substrates of such enzymes.Influence of coadministration of the dual CYP3A4 and CYP2C19 inh